The efficacy and safety of lomitapide as adjunct treatment for adults with homozygous familial hypercholesterolaemia (HoFH) have been confirmed in a phase 3 trial. Given the small number of patients (N = 29), and variations in patient characteristics, examining individual cases provides additional details regarding patient management with lomitapide. Here, we examine the details of the Italian patient cohort in the phase 3 trial.

Individual analysis of patients with HoFH participating in a phase 3 trial with lomitapide: The Italian cohort / Averna, M; Cefalù, A. B; Stefanutti, Claudia; Di Giacomo, S; Sirtori, C. R; Vigna, G.. - In: NMCD. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES. - ISSN 0939-4753. - ELETTRONICO. - 26:1(2016), pp. 36-44-44. [10.1016/j.numecd.2015.11.001]

Individual analysis of patients with HoFH participating in a phase 3 trial with lomitapide: The Italian cohort

STEFANUTTI, Claudia;Di Giacomo, S;
2016

Abstract

The efficacy and safety of lomitapide as adjunct treatment for adults with homozygous familial hypercholesterolaemia (HoFH) have been confirmed in a phase 3 trial. Given the small number of patients (N = 29), and variations in patient characteristics, examining individual cases provides additional details regarding patient management with lomitapide. Here, we examine the details of the Italian patient cohort in the phase 3 trial.
2016
FH; Familial hypercholesterolaemia; HoFH; Homozygous familial hypercholesterolaemia; Lomitapide; Therapy; Adolescent; Adult; Anticholesteremic Agents; Benzimidazoles; Biomarkers; Cholesterol, LDL; Female; Genetic Predisposition to Disease; Humans; Hyperlipoproteinemia Type II; Italy; Male; Middle Aged; Phenotype; Receptors, LDL; Time Factors; Treatment Outcome; Young Adult; Heterozygote; Mutation
01 Pubblicazione su rivista::01a Articolo in rivista
Individual analysis of patients with HoFH participating in a phase 3 trial with lomitapide: The Italian cohort / Averna, M; Cefalù, A. B; Stefanutti, Claudia; Di Giacomo, S; Sirtori, C. R; Vigna, G.. - In: NMCD. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES. - ISSN 0939-4753. - ELETTRONICO. - 26:1(2016), pp. 36-44-44. [10.1016/j.numecd.2015.11.001]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/964812
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